Third generation oral contraception and venous thromboembolism

Hormonal contraception and venous thromboembolism.

BACKGROUND New studies about the influence of hormonal contraception on the risk of venous thromboembolism (VTE) have been published. AIM To evaluate new epidemiological data and to propose clinical consequences. DESIGN A literature survey. METHODS Studies assessing the risk of specific types of hormonal contraception were evaluated, compared and set into a clinical perspective. RESULTS...

Venous Thromboembolism and Hormonal Contraception

Progestin-only contraception and venous thromboembolism.

Combined oral contraceptives (COC) are the most popular contraceptive method in developed countries. Since their introduction there have been numerous changes and modifications in its composition with the aim to improve safety and tolerability while maintaining contraceptive efficacy. Most of the changes have been conducted on the progestin component, since most of the combinations include ethi...

Thrombin generation and venous thromboembolism.

Venous thromboembolism is a chronic and potential fatal disease. Determination of recurrence risk is time-consuming and costly, and sometimes not feasible: many patients carry more than one risk factor, the relevance of some factors with regard to risk of recurrence is unknown, and existence of thus far unknown risk factors must be considered. A laboratory assay that measures multifactorial thr...

[Third generation oral contraceptives and risk of venous thrombosis].

OBJECTIVE To evaluate quantitatively articles that compared effects of second and third generation oral contraceptives on risk of venous thrombosis. DESIGN Meta-analysis. STUDIES Cohort and case-control studies assessing risk of venous thromboembolism among women using oral contraceptives before October 1995. MAIN OUTCOME MEASURES Pooled adjusted odds ratios calculated by a general varian...